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Atropos Health and Every Cure team up to use generative AI to repurpose drugs

Every Cure is a non-profit, founded by Dr. David Fajgenbaum following his brush with a near-fatal rare disease that doctors struggled to diagnose, that finds new uses for existing drugs. Atropos Health, meanwhile, was founded by Dr. Brigham Hyde to eliminate disparity in underserved populations via drug repurposing following his mother’s battle with a rare blood cancer.

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Every Cure Co-Founder Dr. David Fajgenbaum Discusses Finding New Uses for Existing Medicines at Chan Zuckerberg Initiative’s Science in Society Annual Meeting

On September 23rd, Every Cure Co-Founder David Fajgenbaum addressed Chan Zuckerberg Initiative’s Rare as One Network at the Science in Society Annual Meeting about the learnings and opportunities from his work to found and lead Every Cure, a nonprofit drug development organization focused on advancing repurposed treatments. 

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From Bedside to Bench and Back

Research driven by patients with rare diseases is producing faster discoveries and treatments—and challenging long-held assumptions about knowledge production.

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Angiosarcoma Patient Celebrates 7-Year Remission with Pioneering Use of PD-1 Inhibitor: Every Cure Unleashes AI to Ensure No Treatment is Left Overlooked

An Angiosarcoma patient facing a grave prognosis found a lifeline in a repurposed PD-1 inhibitor, a treatment hidden in the medical literature for three years. Every Cure and its partners are building on this breakthrough, deploying innovative AI algorithms that evaluate the potential of every drug for every disease. The efforts have already begun to […]

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Every Cure Co-Founder David Fajgenbaum Addresses The Rare Disease Congressional Caucus!

In a recent address to the Rare Disease Congressional Caucus, David Fajgenbaum, the co-founder of Every Cure, unveiled the organization’s mission to repurposing FDA-approved drugs for diseases that currently have no cure. By leveraging the vast pharmaceutical world’s existing knowledge, Every Cure aims to revolutionize treatment paradigms for thousands who have been told, “We’ve tried […]

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Every Cure Co-founder David Fajgenbaum Presents at Aspen Ideas Health

Aspen, Colorado – David Fajgenbaum, co-founder of Every Cure and physician-scientist at the University of Pennsylvania, unveiled his ‘Big Idea’ to repurpose existing drugs for the treatment of various diseases at the Aspen Idea Health Conference. Fajgenbaum’s personal battle with Castleman Disease during his time as a medical student inspired his mission to explore the […]

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Every Cure Invited to the White House!

Every Cure has raised significant awareness over the last year and engaged with leaders across healthcare and government. In fact, Every Cure Co-Founders Grant Mitchell and David Fajgenbaum (pictured above) met with President Biden’s Chief of Staff, Jeff Zients, in the White House.

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Rare Disease: Could Existing Drugs Turn the Tide?

In September 2022, Fajgenbaum joined forces with longtime friend and fellow doctor Grant Mitchell, MD, and a group of experts at the University of North Carolina and beyond to leverage the power of machine learning to sift through the ocean of existing medical research to connect rare diseases to existing drugs. Their organization is called […]

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In Vivo’s 2023 Rising Leaders: Healthcare Innovators At The Top Of Their Game

David Fajgenbaum is an immunologist and co-founder of Every Cure, a nonprofit organization whose mission is to unlock the full potential of approved medicines to treat every disease possible. The organization, which he launched at the Clinton Global Initiative in 2022, employs AI to search through existing data to identify potential additional indications for approved […]

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Every Cure Announces Breakthrough at STAT Summit

San Francisco, California – David Fajgenbaum, co-founder of Every Cure and physician-scientist at the University of Pennsylvania, announces First Life Saved with AI-Discovered Repurposed Medicine for Castleman Disease with Significant Potential Applications to Treat Other Illnesses

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First Life Saved with AI-Discovered Repurposed Medicine for Castleman Disease with Significant Potential Applications to Treat Other Illnesses

A 50-year-old patient battling life-threatening Castleman disease was provided adalimumab as a treatment of last resort following its identification by AI-guided discovery. Every Cure and its partners are expanding upon this discovery to harness a novel AI algorithm that calculates the potential use of every drug to treat every disease. Initial promising candidates for further […]

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A Man On Fire Fueled By A Mission To Find A Drug For Every Disease

David Fajgenbaum has become a “man on fire,” determined to repurpose as many generic drugs as possible for diseases without approved treatments. Fajgenbaum, whose efforts have been recognized by former President Bill Clinton, spoke with In Vivo about his own patient journey with a disease with no approved treatment and about the Every Cure Foundation, a non-profit […]

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Repurposing Drugs: How One Doctor Saved His Own Life and Hopes to Save Others

Two companies team up to combat rare diseases through drug repurposing, which was heavily informed by one doctor’s experience through unconventionally treating his Castleman disease and (ultimately) saving his own life. Two companies join forces to unlock the hidden potential in existing drugs to save lives suffering from rare diseases. In 2010, Dr. David Fajgenbaum, […]

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How Rare Disease Patients Are Fighting Their Conditions Head-On

As many as 7,000 rare diseases affect 300 million people globally. The vast majority are not well understood, and less than 5 percent have approved treatments. Yet, patients are meeting these challenges head-on. Dr. Fajgenbaum was diagnosed with Castleman disease, a rare disorder that involves an overgrowth of cells in your body’s lymph nodes. The most […]

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Drug Repurposing Provides Big Impact for Patients

Dr. David Fajgenbaum is not afraid to think outside the box and that is what saved his life. While in medical school, the former college athlete suddenly became critically ill. Doctors told him he was suffering from a rare disorder called Castleman disease; his immune system was attacking his vital organs, potentially leading to life-threatening […]

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Chasing Every Cure

It was the night before April Fools’ Day, 2021, when Dr. David Fajgenbaum received the text: President Clinton read your book and would like to talk. Despite the outpouring of praise for his bestselling memoir, Chasing My Cure – an astounding chronicle of Fajgenbaum’s five near-death experiences from Castleman disease and his successful search to […]

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5 Things to Know About Dr. David Fajgenbaum

The Philadelphia physician has the distinction of researching – and solving – his own rare disease. Learn more about this prolific advocate for rare disease patients. Maybe it’s the brush with death that David Fajgenbaum had at a young age that gave him an extra charge of energy, a powerful desire to get things done.

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A Personal Case For Drug Repurposing

For biotechs, the JP Morgan Healthcare Conference is about dealmaking in many forms—securing financing, establishing development partnerships, courting mergers and acquisitions—by wooing would-be partners and investors with a value proposition. Everyone’s in schmooze-and-pitch mode, and everyone’s seeking to capitalize on the momentum the show generates in the news cycle.

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Medable and Every Cure announce partnership for remote clinical trials –

Medable has announced a collaboration with non-profit Every Cure for conducting global, remote clinical trials for drug repurposing candidates. Every Cure was officially launched, in collaboration with the Clinton Global Initiative, in September to scale up a new ‘drug repurposing’ research approach for identifying rare disease treatments.

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How a Doctor Faced Down His Rare Disease

This week, an exciting interview from our archive airs on Oct. 8, 2022. A healthy young medical student, David Fajgenbaum, had been a student athlete in college and maintained his extraordinary level of fitness through much of medical school. Because of his enthusiasm and athleticism, his friends called him The Beast. When he suddenly found […]

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