Grant Mitchell discusses Every Cure’s mission, challenges in health tech entrepreneurship, impact assessment, future innovations, and advice for aspiring entrepreneurs.

Rare diseases often require innovative treatments, but not always brand-new ones. This research nonprofit deploys AI as a matchmaker between doctors and existing medications.

The alliance will focus specifically on enhancing clinical trials and their outcomes to boost trial success rates and the efficient use of capital by drug developers.

ABC News’ Rebecca Jarvis looks at artificial intelligence’s role in the medical field and how it’s allowing doctors to expand their research and make decisions for patients.

We talk with a doctor who discovered a cure for rare diseases with the help of artificial intelligence.

A nonprofit that seeks to repurpose approved drugs for new indications will receive more than $48 million from the U.S. Advanced Research Projects Agency for Health to supercharge its work, the agency said on 28 February.

Over the past few years, Every Cure has developed a blueprint for an AI-powered platform that can do what humans can’t — match thousands of diseases with thousands of drugs.

Every Cure, cofounded by Penn’s David Fajgenbaum, received a three-year $48 million federal contract to develop an AI tool for rare diseases.

Agency backs non-profit’s agnostic approach to drug repurposing with $48.3M

ABC News chief medical correspondent Dr. Jen Ashton discusses Every Cure’s AI platform that aims to match FDA-approved drugs with diseases currently lacking approved treatments.

The White House is hoping to use AI to match already approved drugs with untreated diseases. The federal government is giving nonprofit Every Cure nearly $50 million to develop the technology.

New database aims to match rare-disease patients with drugs on pharmacy shelves

The three-year, $48.3 million ARPA-H contract will supercharge Every Cure’s work to identify existing medicines that can be repurposed to treat currently untreated diseases.

Dr. David Fajgenbaum saved his own life by tracking down a generic drug that cured his rare and deadly disease. Now with nonprofit Every Cure, he’s seeking cures for the estimated 9,000+ untreatable rare diseases — and fast.

Every Cure is a non-profit, founded by Dr. David Fajgenbaum following his brush with a near-fatal rare disease that doctors struggled to diagnose, that finds new uses for existing drugs. Atropos Health, meanwhile, was founded by Dr. Brigham Hyde to eliminate disparity in underserved populations via drug repurposing following his mother’s battle with a rare blood cancer.

This Challenge is a bold initiative to incubate innovations by healthcare start-ups and entrepreneurs across disciplines and sectors to responsibly and equitably use artificial intelligence (AI).

AI has also enabled the discovery of a new application for an existing drug in treating a rare disease, iMCD. This development represents a significant breakthrough, showcasing the power of AI in identifying and repurposing existing drugs for new therapeutic uses.

The Fierce 50 special report shines a spotlight on those who are making a significant impact and driving progress in the pharmaceutical, healthcare and biotech industries

Since the advent of modern medicine, the scientific community has developed more than 3,000 drugs for thousands of diseases. Despite significant progress, there are more than 6,500 rare diseases without a single approved treatment.

He’s alive thanks to a repurposed drug. Now his dream is to find cures for millions of people from among drugs we already have.

While rare diseases are defined as conditions affecting fewer than 200,000 individuals, the shortage of rare disease treatments in the United States is a significant and pressing issue that affects countless individuals and their families who are grappling with often life-threatening medical conditions

Research driven by patients with rare diseases is producing faster discoveries and treatments—and challenging long-held assumptions about knowledge production.

Have you read the story of David Fajgenbaum, a physician who was diagnosed with the rare disease called Castleman disease?

A patient’s life was saved after researchers at the University of Pennsylvania, Castleman Disease Collaborative Network, Medidata, and Every Cure, used artificial intelligence to use an existing drug to treat idiopathic multicentric Castleman disease (iMCD).

Of course, AI was on everyone’s minds at the conference. However, it was the proof points and examples shared by leaders from multiple organizations that signaled the dramatic surge in impact.

The adoption of AI is accelerating across the entire CRO space as we start to explore the benefits of the tech. Whether being utilised for CRO expansion, streamlined clinical trials, better data analysis or another application we’ve yet to discover.

Aspen, Colorado – David Fajgenbaum, co-founder of Every Cure and physician-scientist at the University of Pennsylvania, unveiled his ‘Big Idea’ to repurpose existing drugs for the treatment of various diseases at the Aspen Idea Health Conference. Fajgenbaum’s personal battle with Castleman Disease during his time as a medical student inspired his mission to explore the […]

We are very excited to have Dr. David Fajgenbaum as our student-selected keynote speaker on this momentous occasion of our 50th commencement ceremony. His impressive and lofty goals and accomplishments will serve as a lasting inspiration to our students and anyone in attendance,” stated Dr. David Guzick, Chancellor of LSU Health Shreveport.

Miami, Florida – David Fajgenbaum, co-founder of Every Cure, delivered a presentation at the Elevate Prize’s Make Good Famous Summit, sharing his journey with illness and his mission to repurpose existing drugs for the treatment of various diseases.  In a moving speech at the Make Good Famous Summit in Miami, David Fajgenbaum, co-founder of Every […]

In September 2022, Fajgenbaum joined forces with longtime friend and fellow doctor Grant Mitchell, MD, and a group of experts at the University of North Carolina and beyond to leverage the power of machine learning to sift through the ocean of existing medical research to connect rare diseases to existing drugs. Their organization is called […]

David Fajgenbaum is an immunologist and co-founder of Every Cure, a nonprofit organization whose mission is to unlock the full potential of approved medicines to treat every disease possible. The organization, which he launched at the Clinton Global Initiative in 2022, employs AI to search through existing data to identify potential additional indications for approved […]

San Francisco, California – David Fajgenbaum, co-founder of Every Cure and physician-scientist at the University of Pennsylvania, announces First Life Saved with AI-Discovered Repurposed Medicine for Castleman Disease with Significant Potential Applications to Treat Other Illnesses

Fajgenbaum was having his last rites read to him, and his family braced for his death from Castleman disease, a rare inflammatory illness that impacts the lymph nodes and can severely damage other organs.

About a decade ago, David Fajgenbaum thought his life was over. He was a young, bright physician hoping to work in oncology in remembrance of his mother, who died of brain cancer a few years earlier. Fajgenbaum was having his last rites read to him, and his family braced for his death from Castleman disease, […]

David Fajgenbaum has become a “man on fire,” determined to repurpose as many generic drugs as possible for diseases without approved treatments. Fajgenbaum, whose efforts have been recognized by former President Bill Clinton, spoke with In Vivo about his own patient journey with a disease with no approved treatment and about the Every Cure Foundation, a non-profit […]

Two companies team up to combat rare diseases through drug repurposing, which was heavily informed by one doctor’s experience through unconventionally treating his Castleman disease and (ultimately) saving his own life. Two companies join forces to unlock the hidden potential in existing drugs to save lives suffering from rare diseases. In 2010, Dr. David Fajgenbaum, […]

David Fajgenbaum, MD, was a college football player at Georgetown University in 2004 when his mother passed away from cancer. The loss inspired the athlete to become a doctor himself: “I wanted to treat patients in memory of my mom,” he says. But three years into medical school, the then-25-year-old’s health took a turn for […]

As many as 7,000 rare diseases affect 300 million people globally. The vast majority are not well understood, and less than 5 percent have approved treatments. Yet, patients are meeting these challenges head-on. Dr. Fajgenbaum was diagnosed with Castleman disease, a rare disorder that involves an overgrowth of cells in your body’s lymph nodes. The most […]

Dr. David Fajgenbaum is not afraid to think outside the box and that is what saved his life. While in medical school, the former college athlete suddenly became critically ill. Doctors told him he was suffering from a rare disorder called Castleman disease; his immune system was attacking his vital organs, potentially leading to life-threatening […]

It was the night before April Fools’ Day, 2021, when Dr. David Fajgenbaum received the text: President Clinton read your book and would like to talk. Despite the outpouring of praise for his bestselling memoir, Chasing My Cure – an astounding chronicle of Fajgenbaum’s five near-death experiences from Castleman disease and his successful search to […]

The Philadelphia physician has the distinction of researching – and solving – his own rare disease. Learn more about this prolific advocate for rare disease patients. Maybe it’s the brush with death that David Fajgenbaum had at a young age that gave him an extra charge of energy, a powerful desire to get things done.

For biotechs, the JP Morgan Healthcare Conference is about dealmaking in many forms—securing financing, establishing development partnerships, courting mergers and acquisitions—by wooing would-be partners and investors with a value proposition. Everyone’s in schmooze-and-pitch mode, and everyone’s seeking to capitalize on the momentum the show generates in the news cycle.

Medable has announced a collaboration with non-profit Every Cure for conducting global, remote clinical trials for drug repurposing candidates. Every Cure was officially launched, in collaboration with the Clinton Global Initiative, in September to scale up a new ‘drug repurposing’ research approach for identifying rare disease treatments.

This week, an exciting interview from our archive airs on Oct. 8, 2022. A healthy young medical student, David Fajgenbaum, had been a student athlete in college and maintained his extraordinary level of fitness through much of medical school. Because of his enthusiasm and athleticism, his friends called him The Beast. When he suddenly found […]

A new nonprofit backed by the Clinton Global Initiative aims to identify generic drugs that could help people with rare diseases. Every Cure is based on the concept that every drug on the market has multiple effects on the body, not just the one or two that first earned its approval.

A new nonprofit backed by the Clinton Global Initiative aims to identify generic drugs that could help people with rare diseases. Every Cure is based on the concept that every drug on the market has multiple effects on the body, not just the one or two that first earned its approval.

Every drug on the market has multiple effects on the body, not just the one or two that won it approval. A new nonprofit aims to exploit those other effects to help patients with rare diseases.