Every Cure Repurposing Portfolio

  • Repurposed Treatments

Every Cure has made significant strides in advancing 18 repurposed treatments for conditions such as idiopathic multicentric Castleman Disease (iMCD), Angiosarcoma and COVID-19. The list below highlights the attributions in addition to the history of the drug. The non-profit is working toward identifying 100 promising repurposing opportunities over the next five years, with a goal to advance 25 into clinical use.



Steps to Drug Repurposing

  • Step 1
  • Step 2
  • Step 3
  • Step 4
  • Step 5
  • Step 6
  • Step 7
  • Step 8

Repurposing Analysis

This approach means that we don’t just hope that the right study will be conceptualized and applied for by a researcher. We identify the right study and then recruit the right researcher with the right skill set to perform the study and provide the necessary funding and tissue samples. Most importantly, any idea can potentially turn into a study rather than just ideas conceived by the researchers that can perform the studies.

Identify Target

Match to Drug

Pre-Clinical Validation

After selecting the top priority project , recruiting the foremost expert in that field , and obtaining the necessary funds  and samples, Every Cure assists with all aspects of successful execution of the study.

We establish a research agreement, coordinate contracts among collaborators, provide project management support, and contribute scientific advice throughout the process.

Treat/Track Patients

For every study, Every Cure works with patients and physicians around the world to coordinate obtaining the necessary samples (e.g., blood, saliva, left over lymph node tissue, etc). Obtaining high-quality samples is a major challenge in rare disease research.

Every Cure proactively seeks to obtain tissue samples for future studies, because researchers can’t do research without patient samples. Every Cure international community of researchers needs samples from patients so that we can continue to drive forward our search for a cure!  These samples help us to better characterize this disease and will lead to greater knowledge about current and potential treatments.

Clinical Trial

Treatment Guidelines

Widespread Use

After performing the studies and publishing the data, Every Cure works to ensure these findings are disseminated among researchers, physicians, patients and loved ones around the world as quickly as possible. We accomplish this through physician/researcher meetings, Patient Summits, online portals for patients, physicians and researchers, social media and online Every Cure resources.

When battling a rare disease, it is essential new findings are shared with a wide audience as quickly as possible.

Then,Every Cure shares these results with the medical community to inspire new ideas for research and the cycle repeats.

Repurposed Treatments

  • Step 1

    Repurposing Analysis

  • Step 2

    Identify Target

  • Step 3

    Match to Drug

  • Step 4

    Pre-Clinical Validation

  • Step 5

    Treat/Track Patients

  • Step 6

    Clinical Trial

  • Step 7

    Treatment Guidelines

  • Step 8

    Widespread Use

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